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Linagliptin, a DPP-4 inhibitor, has been reported to upregulate eNOS and restore endothelium-dependent vasodilation (64, 65)
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However, another study found a significantly lowered risk of developing glaucoma and ocular hypertension in all patient groups receiving the treatment at 1, 2, and 3 years (41%, 50%, and 41% risk reduction, respectively) (Muayad et al., 2024)
